The 21-year-old is suspended for yellow card accumulation and has been left out of the squad for the trip.
Boateng scored a hat-trick against Barcelona last weekend in a 5-4 win over the Blaugrana.
The former Ghana U20 star has been handed a call up to play for the Black Stars in upcoming international friendlies against Iceland and Japan.
He has scored 6 goals in 25 La Liga appearances this season.
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